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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN3
All Species:
20.61
Human Site:
T357
Identified Species:
32.38
UniProt:
Q6P5Z2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P5Z2
NP_037487.2
889
99421
T357
A
E
Q
S
W
D
Q
T
F
V
I
P
L
E
R
Chimpanzee
Pan troglodytes
XP_001159776
886
99121
T357
A
E
Q
S
W
D
Q
T
F
V
I
P
L
E
R
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
T470
A
K
Q
S
W
D
Q
T
F
V
I
P
L
E
R
Dog
Lupus familis
XP_548434
951
104664
M419
A
K
Q
S
W
D
Q
M
F
I
V
P
L
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8K045
878
97863
S350
A
E
K
S
W
D
Q
S
F
I
I
S
L
D
R
Rat
Rattus norvegicus
O08874
985
112050
K421
S
N
Q
S
W
D
Q
K
F
T
L
E
L
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
N457
S
K
Q
G
W
D
Q
N
F
L
I
P
L
E
R
Chicken
Gallus gallus
XP_422357
1013
114806
K446
S
N
Q
S
W
D
Q
K
F
T
L
E
L
D
R
Frog
Xenopus laevis
Q7ZX15
486
56292
L64
F
S
V
A
E
C
Q
L
M
K
T
E
R
P
R
Zebra Danio
Brachydanio rerio
XP_697542
940
106140
S408
S
K
D
A
W
N
Q
S
F
S
I
E
L
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
I212
E
I
L
S
S
L
G
I
S
P
D
K
Q
Q
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
L269
C
D
H
C
G
S
M
L
Y
G
L
I
N
Q
G
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
R267
N
V
R
W
K
D
Q
R
S
L
C
A
V
K
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
S384
L
T
L
G
F
H
K
S
S
Q
I
E
R
K
Q
Red Bread Mold
Neurospora crassa
P87253
1142
127954
Y456
K
E
E
V
H
E
M
Y
G
H
K
F
V
Q
K
Conservation
Percent
Protein Identity:
100
97.7
81.5
84.2
N.A.
83.2
49.9
N.A.
64.2
48.9
26.2
52.2
N.A.
28
N.A.
29.1
41.5
Protein Similarity:
100
97.8
82.9
87.6
N.A.
88.4
63.6
N.A.
72.9
63
36.6
67.6
N.A.
41.5
N.A.
43.9
58.2
P-Site Identity:
100
100
93.3
73.3
N.A.
66.6
53.3
N.A.
66.6
53.3
13.3
46.6
N.A.
6.6
N.A.
0
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
73.3
N.A.
86.6
73.3
20
80
N.A.
13.3
N.A.
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
27.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
43.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
0
14
0
0
0
0
0
0
0
7
0
0
0
% A
% Cys:
7
0
0
7
0
7
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
7
7
0
0
60
0
0
0
0
7
0
0
20
0
% D
% Glu:
7
27
7
0
7
7
0
0
0
0
0
34
0
40
0
% E
% Phe:
7
0
0
0
7
0
0
0
60
0
0
7
0
0
7
% F
% Gly:
0
0
0
14
7
0
7
0
7
7
0
0
0
0
7
% G
% His:
0
0
7
0
7
7
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
7
0
14
47
7
0
0
0
% I
% Lys:
7
27
7
0
7
0
7
14
0
7
7
7
0
14
7
% K
% Leu:
7
0
14
0
0
7
0
14
0
14
20
0
60
0
0
% L
% Met:
0
0
0
0
0
0
14
7
7
0
0
0
0
0
0
% M
% Asn:
7
14
0
0
0
7
0
7
0
0
0
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
7
0
34
0
7
7
% P
% Gln:
0
0
47
0
0
0
74
0
0
7
0
0
7
20
7
% Q
% Arg:
0
0
7
0
0
0
0
7
0
0
0
0
14
0
67
% R
% Ser:
27
7
0
54
7
7
0
20
20
7
0
7
0
0
0
% S
% Thr:
0
7
0
0
0
0
0
20
0
14
7
0
0
0
0
% T
% Val:
0
7
7
7
0
0
0
0
0
20
7
0
14
0
0
% V
% Trp:
0
0
0
7
60
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _